ImmunoglobulinλGene Rearrangement Can PrecedeκGene Rearrangement
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چکیده
منابع مشابه
Immunoglobulin λ Gene Rearrangement Can Precede κ Gene Rearrangement
Immunoglobulin genes are generated during differentiation of B lymphocytes by joining gene segments. A mouse pre-B cell contains a functional immunoglobulin heavy-chain gene, but no light-chain gene. Although there is only one heavy-chain locus, there are two light-chain loci: kappa and lambda. It has been reported that kappa loci in the germ-line configuration are never (in man) or very rarely...
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ژورنال
عنوان ژورنال: Developmental Immunology
سال: 1990
ISSN: 1044-6672
DOI: 10.1155/1990/56014